HCID 54250094, compound → HCID 53753805, compound

HRID 635466Notes

Reaction equation

HRID 635466 reaction equation
[C:1]([O:4][CH2:5][C:6]([NH:26][C:27](=[O:29])[CH3:28])([CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18]CC1C=CC=CC=1)[CH2:7][CH2:8][CH3:9])(=[O:3])[CH3:2]>C(O)C.[C].[Pd]>[C:1]([O:4][CH2:5][C:6]([NH:26][C:27](=[O:29])[CH3:28])([CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[OH:18])[CH2:7][CH2:8][CH3:9])(=[O:3])[CH3:2]

Participants

4

Reactant 1

HCID 54250094HCID 54250094, compound

Product 1

HCID 53753805HCID 53753805, compoundYield 93.4%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

To a solution of 2-acetamido-2-(2-(2-benzyloxyphenyl)ethyl)pentyl acetate (0.90 g) in ethanol (45 ml), 10% palladium-carbon (0.40 g) was added and the mixture was subjected to catalytic reduction at room temperature for 6 hours. Catalyst was filtered off from the reaction solution and the solvent was distilled away under reduced pressure to give the subject compound (0.65 g).

Workup

  1. filtrationCatalyst was filtered off from the reaction solution
  2. distillationthe solvent was distilled away under reduced pressure

Sources & evidence

ORD record
ord-0d66c46721ab4f8c8c8baf1297b99e4d
Source dataset
uspto-grants-2001_02
Patent number
US06187821B1

Reaction notes

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