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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 635479Generated: October 30, 2026

Diethyl ethylmalonate → 2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

https://huagongshe.com/reaction/635479

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl ethylmalonateHCID 8610—
ReactantHCID 53718772HCID 53718772—
Product2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanolHCID 22618796—

Reaction Steps

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is treated in the same manners as working example 79 and then working example 80 to give the subject compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06187821B1
Source datasetuspto-grants-2001_02
ORD IDord-df0000f5f6fc4f178a75fe6914b3b386
Source noteuspto-grants-2001_02