HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(2-Chloro-4-fluorophenyl)acetamide → HCID 86608198, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(2-Chloro-4-fluorophenyl)acetamide | HCID 2773716 | — |
| Edukt | 2-(2-Fluorophenyl)acetamide | HCID 12269175 | — |
| Produkt | HCID 86608198 | HCID 86608198 | — |
Reaktionsschritte
(±)-Trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1yl)-4-(2-fluorophenyl)pyrrolidine-2,5-dione was prepared according to Example 40 replacing 2-chloro-4-fluorophenylacetamide with 2-fluorophenylacetamide. Yield 30.6 mg, 8.8%. 1H NMR (DMSO-d6) 400 MHz δ: 11.64 (s, 1H), 7.36 (m, 3H), 7.17 (m, 3H), 6.84 (m, 2H), 4.44 (d, 1H, J=7.2 Hz), 4.40 (d, 1H, J=7.6 Hz), 4.10 (s, 2H), 2.88 (s, 2H), 2.09 (s, 2H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09447088B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-88c06e7ed98f4ea6a18638ef5c20895f |
| Quellennotiz | uspto-grants-2016_09 |