HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorobenzaldehyde → 2-(3-chlorophenyl)-ethenyl-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorobenzaldehyde | HCID 11477 | — |
| Reactant | 1-(6,7,8,9-Tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-ethanone | HCID 21256456 | — |
| Product | 2-(3-chlorophenyl)-ethenyl-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl methanone | HCID 86756427 | — |
Reaction Steps
1-(6,7,8,9-Tetrahydro-5H-cyclohept[d]-imidazo[2,1-b]thiazol-3-yl ethanone (Formula N-4), 1.87 g, and 3-chlorobenzaldehyde (0.216 g) were condensed following non-critical variations of Example 15 to provide 6,7,8,9-Tetrahydro-[2-(3-chlorophenyl)-ethenyl-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl methanone (Formula N-5, X=3-chloro), (2.72 g), m.p. 137-139°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191124B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-68c71490665b44a189993c5eade27984 |
| Source note | uspto-grants-2001_02 |