HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → 3-[3-(2,3-Dimethylimidazo[2,1-b]thiazol-5-yl)-3-oxo-1-propenyl]phenyl-4-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | o-Toluenesulfonyl chloride | HCID 8623 | — |
| Reactant | Benzaldehyde, 3-amino- | HCID 74366 | — |
| Reactant | m-Toluenesulphonamide | HCID 74697 | — |
| Reactant | 2,3-Dimethylimidazo[2,1-b]thiazol-5-yl ethanone | HCID 21256445 | — |
| Product | 3-[3-(2,3-Dimethylimidazo[2,1-b]thiazol-5-yl)-3-oxo-1-propenyl]phenyl-4-methylbenzenesulfonamide | HCID 86756428 | — |
Reaction Steps
1-(2,3-Dimethylimidazo[2,1-b]-thiazol-5-yl ethanone (Formula N′-1), 0.97 g, was condensed with the 3-toluensulfonamide of benzaldehyde, m.p. 126-127°, prepared from toluene sulfonyl chloride and 3-aminobenzaldehyde, according to non-critical modifications of PREPARATION 15 to provide pure (E)-N-[3-[3-(2,3-Dimethylimidazo[2,1-b]thiazol-5-yl)-3-oxo-1-propenyl]phenyl-4-methylbenzenesulfonamide, m.p. 236-237°, Formula N′-2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191124B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-ed899c7d24cd4a589abc1bab3ad8f41e |
| Source note | uspto-grants-2001_02 |