HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxybenzaldehyde → 3-(4-Methoxyphenyl)-1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-2-propene-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Reactant | 1-(6,7,8,9-Tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-ethanone | HCID 21256456 | — |
| Product | 3-(4-Methoxyphenyl)-1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-2-propene-1-one | HCID 70058543 | — |
Reaction Steps
1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-ethanone (Formula N-4), 0.44 g, and anisaldehyde (0.5 mL) were condensed according to non-critical variations in PREPARATION 15 to produce 3-(4-Methoxyphenyl)-1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-2-propene-1-one, 0.65 g, (Formula N-5, X=4-methoxy), m.p. 180-187°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191124B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-81ead6fcc7544c1d8815bcc988788dcc |
| Source note | uspto-grants-2001_02 |