2-Naphthalenecarboxaldehyde → HCID 53698518, compound

HRID 635878Notes

Reaction equation

HRID 635878 reaction equation
[N:1]1[CH:2]=[C:3]([C:14](=[O:16])[CH3:15])[N:4]2[C:8]3[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:7]=3[S:6][C:5]=12.[CH:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[CH:19][C:18]=1[CH:27]=O>>[CH:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[CH:19][C:18]=1[CH:27]=[CH:15][C:14]([C:3]1[N:4]2[C:5]([S:6][C:7]3[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][C:8]=32)=[N:1][CH:2]=1)=[O:16]

Participants

3

Reactant 2

HCID 62012-NaphthalenecarboxaldehydeHCID 212564561-(6,7,8,9-Tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-ethanone

Product 1

HCID 53698518HCID 53698518, compound

Procedure

1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)ethanone (Formula O-1), 1.37 g, was condensed with 2-napthaldehyde by non-critical variations of EXAMPLE 15 to yield 3-(2-Napthalenyl)-1-(6,7,8,9-tetrahydro-5H-cyclohept[d]imidazo[2,1-b]thiazol-3-yl)-2-propene-1-one (Formula O-2), 2.24 g, m.p. 185-188°.

Sources & evidence

ORD record
ord-7a329372e28a402a8be2de4f6ec40fe4
Source dataset
uspto-grants-2001_02
Patent number
US06191124B1

Reaction notes

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