HCID 21256732, compound → HCID 135549343, compound

HRID 635894Notes

Reaction equation

HRID 635894 reaction equation
[C:1]1([CH:7]2[CH2:12][CH2:11][N:10]([CH2:13][CH2:14][CH2:15][CH2:16][OH:17])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([O:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]2[N:37]=[C:36]([CH3:38])[N:35]=[C:34]([Cl:39])[CH:33]=2)=[CH:28][CH:27]=1)C1C=CC=CC=1>>[ClH:39].[OH:25][C:26]1[CH:27]=[CH:28][C:29]([C:32]2[CH:33]=[C:34]([O:17][CH2:16][CH2:15][CH2:14][CH2:13][N:10]3[CH2:9][CH2:8][CH:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[CH2:12][CH2:11]3)[N:35]=[C:36]([CH3:38])[N:37]=2)=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 21256732HCID 21256732, compoundHCID 21256809HCID 21256809, compound

Product 1

HCID 135549343HCID 135549343, compound

Procedure

Using 4-(4-phenylpiperidino)-1-butanol and 6-(4-benzyloxyphenyl)-4-chloro-2-methylpyrimidine, the procedure of Reference Example 25, which appears hereinafter, was otherwise followed to provide the title compound. m.p. 182-183° C.

Sources & evidence

ORD record
ord-1ca396d7732e49118efc185f8a3c34a6
Source dataset
uspto-grants-2001_02
Patent number
US06191149B1

Reaction notes

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