HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Naphthalenesulfonyl chloride → 3-(1,2,3,5,8,8a-Hexahydro-7-indolizinyl)-1-(1-naphthalenesulfonyl)-5-azaindole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Naphthalenesulfonyl chloride | HCID 66560 | — |
| Edukt | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Edukt | 3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-1H-5-Azaindole | HCID 10130974 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 3-(1,2,3,5,8,8a-Hexahydro-7-indolizinyl)-1-(1-naphthalenesulfonyl)-5-azaindole | HCID 9954366 | — |
Reaktionsschritte
from 3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-1H-5-Azaindole (10 mg, 0.0418 mmol), 1-naphthalenesulfonyl chloride (20 mg, 0.088 mmol) and 1M NaN(TMS)2 (100 μL, 0.10 mmol) in THF (0.5 mL) at RT.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06191141B1 |
| Quelldatensatz | uspto-grants-2001_02 |
| ORD ID | ord-f07fcf61a5d24dc2b4770c342cc58fef |
| Quellennotiz | uspto-grants-2001_02 |