HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichlorobenzoyl chloride → 1-(2,6-Dichlorobenzoyl)-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-5-azaindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichlorobenzoyl chloride | HCID 78392 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | 3-(1-Methyl-1,2,3,6-tetrahydro-4-pyridinyl)-5-azaindole | HCID 9794365 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-(2,6-Dichlorobenzoyl)-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-5-azaindole | HCID 9800320 | — |
Reaction Steps
from 3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)5-azaindole (20 mg, 0.094 mmol), 2,6-dichlorobenzoyl chloride (27 μL, 0.188 mmol) and 1M NaN(TMS)2 (250 μL, 0.25 mmol) in THF (1 mL) at RT.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191141B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-c59ccdb5b6954c15b3a3c196bd15545e |
| Source note | uspto-grants-2001_02 |