HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63597Generated: October 29, 2026
Potassium Carbonate → HCID 70952154, compound
https://huagongshe.com/reaction/63597
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | 1-Benzenesulfonyl-5-bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine | HCID 24229240 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Toluene ethanol | HCID 21863594 | — |
| Product | HCID 70952154 | HCID 70952154 | — |
Reaction Steps
To a solution of 3-iodo-5-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (250 mg, 0.54 mmol) in a 3:1 toluene/ethanol mixture (17 ml) are added benzene boronic acid (65 mg, 0.54 mmol), K2CO3 (1.6 ml of 2 M solution in water, 3.20 mmol) and Pd(PPh3)4 (1.5 mol %) and the reaction is heated at 110° C. for 3.5 hours under argon.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09447093B2 |
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| Source dataset | uspto-grants-2016_09 |
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| ORD ID | ord-61dfe940b77f4133ba5518c354d86172 |
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| Source note | uspto-grants-2016_09 |
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