反应详情

The product from Example 30B (6.4 g, 26 mmol) in chloroform (300 mL) was treated with manganese dioxide (4.5 g, 50 mmol), stirred overnight, treated with an additional portion of manganese dioxide (2.25 g), stirred overnight, filtered and concentrated. The residue was purified by flash chromatography over silica gel (ethyl acetate/hexane 1:4) to provide 1.9 g of the title compound.

1. stirringstirred overnight
2. filtrationfiltered
3. concentrationconcentrated
4. customThe residue was purified by flash chromatography over silica gel (ethyl acetate/hexane 1:4)