3-Aminocyclohex-2-en-1-one → HCID 10223145, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of thiopyran-3,5-dione (Fehnel, E. A., J. Amer. Chem. Soc., (1955), 77, 4241-4244) (0.12 g, 1.0 mmol), 3-bromo-4-fluorobenzaldehyde (0.20 g, 1.0 mmol), 3-amino-2-cyclohexene-1-one (0.11 g, 1.0 mmol) and ethanol (5 mL) was heated to 80° C. in a sealed tube for 60 hours and cooled to ambient temperature. The resulting solid was collected by filtration, washed with ethanol and fried for 16 hours under high vacuum to provide the title compound (0.13 g).

Provenance & Evidence