HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylpentanoic acid → N-(3-methylpentanoyl)-L-alanine Isobutyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylpentanoic acid | HCID 7755 | — |
| Reactant | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| Product | N-(3-methylpentanoyl)-L-alanine Isobutyl Ester | HCID 15481764 | — |
Reaction Steps
Following General Procedure B′ and using 3-methylpentanoic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example B′ above), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191166B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-0e42019d61484392b2b3277167b05ca9 |
| Source note | uspto-grants-2001_02 |