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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 636110Generated: October 30, 2026

o-Tolylacetic acid → 2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/636110

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-Tolylacetic acidHCID 69519—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 54573498—

Reaction Steps

Following General Procedure I′ above and using 2-methylphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06191166B1
Source datasetuspto-grants-2001_02
ORD IDord-0819d5b74e6e46818f9a974cbafd85fe
Source noteuspto-grants-2001_02