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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 636112Generated: October 27, 2026

2-(4-Fluorophenyl)acetic acid → 2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/636112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluorophenyl)acetic acidHCID 9837—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl esterHCID 54144399—

Reaction Steps

Following General Procedure I′ above and using 4-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06191166B1
Source datasetuspto-grants-2001_02
ORD IDord-a4802dab3b344e84977e057151c66b69
Source noteuspto-grants-2001_02