HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)benzeneacetic acid → 2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)benzeneacetic acid | HCID 67695 | — |
| Reactant | Isobutyl 2-aminobutyrate | HCID 13743360 | — |
| Product | 2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl Ester | HCID 15481772 | — |
Reaction Steps
Following General Procedure I′ above and using 3-trifluoromethylphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191166B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-c09321f8014d45849539ebd77bfe11b2 |
| Source note | uspto-grants-2001_02 |