HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Difluorophenylacetic acid → N-[(3,5-difluorophenyl)acetyl]alanine iso-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Difluorophenylacetic acid | HCID 145424 | — |
| Reactant | 2-methylpropyl (2S)-2-aminopropanoate | HCID 13743556 | — |
| Product | N-[(3,5-difluorophenyl)acetyl]alanine iso-butyl ester | HCID 22894975 | — |
Reaction Steps
Following General Procedure I′ above, and using 3,5-difluorophenylacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191166B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-c175269e3ecf4b9ab3a14192e634c2d4 |
| Source note | uspto-grants-2001_02 |