Cyclopropaneacetic acid → N-(Cyclopropylacetyl)-L-alanine Methyl Ester

HRID 636142Notes

Reaction equation

[CH:1]1([CH2:4][C:5]([OH:7])=O)[CH2:3][CH2:2]1.Cl.[CH3:9][O:10][C:11](=[O:15])[C@H:12]([CH3:14])[NH2:13]>>[CH3:9][O:10][C:11](=[O:15])[C@H:12]([CH3:14])[NH:13][C:5](=[O:7])[CH2:4][CH:1]1[CH2:2][CH2:3]1

Participants

Reactant 2

HCID 138440Cyclopropaneacetic acid

HCID 2733257Alanine methyl ester hydrochloride

Product 1

HCID 53934383N-(Cyclopropylacetyl)-L-alanine Methyl Ester

Procedure

Following General Procedure D′ above, and using cyclopropylacetic acid (Aldrich) with L-alanine methyl ester hydrochloride (Sigma), the title compound was prepared.

Sources & evidence

ORD record: ord-2d865b89f4554489b4a2d1f29c114b15
Source dataset: uspto-grants-2001_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06191166B1

Reaction notes

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