反应详情

A mixture of 3-amino-2-cyclohexen-1-one (25.0 g, 224.9 mmol) and methyl propiolate (23.6 g, 281 mmol) was heated to reflux for 1 h. The mixture was cooled and the solid was collected by filtration, washing with THF, to give 7.8 g (21%) of the title compound as a yellow solid. [M+H] calc'd for C9H9NO2, 164. found 164.

1. temperaturewas heated
2. temperatureto reflux for 1 h
3. temperatureThe mixture was cooled
4. filtrationthe solid was collected by filtration
5. washwashing with THF