HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl L-valinate hydrochloride → N-[N-(3-Nitrophenylacetyl)-L-alaninyl]-L-valine Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl L-valinate hydrochloride | HCID 87181 | — |
| Reactant | N-(3-Nitrophenylacetyl)-L-alanine | HCID 53788870 | — |
| Solvent | Chloroform methanol | HCID 21584188 | — |
| Product | N-[N-(3-Nitrophenylacetyl)-L-alaninyl]-L-valine Ethyl Ester | HCID 22895023 | — |
Reaction Steps
Following General Procedure C and using N-(3-nitrophenylacetyl)-L-alanine (from Example D11 above) and L-valine ethyl ester hydrochloride (Aldrich), the title compound was prepared as a solid. The reaction was monitored by tlc (Rf=0.2 in 97:3 CHCl3/MeOH) and the product was purified by silica gel chromatography using 97:3 CHCl3/MeOH as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191166B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-0448beb2977b4d008480e8c5d147417f |
| Source note | uspto-grants-2001_02 |