Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 636233Generated: October 29, 2026

(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid → HCID 22894963, compound

https://huagongshe.com/reaction/636233

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acidHCID 12135350—
ReactantHCID 22492131HCID 22492131—
ProductHCID 22894963HCID 22894963—

Reaction Steps

Following General Procedure C and using N-(3,5-difluorophenylacetyl)-L-alanine (from Example B2 above) and methyl 2-amino-2-(2-methylthiazol-4-yl)acetate (prepared from N-Boc-2-amino-2-(2-methylthiazol-4-yl)acetic acid [CAS 105381-90-6] using General Procedure H above), the title compound was prepared as a solid. The product was purified by tituration using Et2O/hexanes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06191166B1
Source datasetuspto-grants-2001_02
ORD IDord-b98fdc4baad9456482d84cdc60afadd9
Source noteuspto-grants-2001_02