HuagongsheHuagongshe Chemistry Print Report · For research reference only
Leucine methyl ester hydrochloride → N-[N-(Phenylacetyl)-L-alaninyl]-L-leucine Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Leucine methyl ester hydrochloride | HCID 2723695 | — |
| Reactant | N-(Phenylacetyl)-L-alanine | HCID 7004640 | — |
| Product | N-[N-(Phenylacetyl)-L-alaninyl]-L-leucine Methyl Ester | HCID 9923756 | — |
Reaction Steps
Following General Procedure A and using N-(phenylacetyl)-L-alanine (from Example B1 above) and L-leucine methyl ester hydrochloride (Aldrich), the title compound was prepared as a solid (mp=102.5-105° C.). The reaction was monitored by tlc (Rf=0.25 in 50% EtOAc/hexanes).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06191166B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-67148490ef3341ba98707b3c7344750d |
| Source note | uspto-grants-2001_02 |