Thiophenol → 6-(1-Anthraquinonecarbonyl)-3,6,10,16-tetraazabicyclo-[10.3.1]hexadeca-1(16),12,14-triene

Participants

Reaction Steps

The title compound was prepared following the procedures illustrated above in Example 78 using 6-(1-anthraquinonecarbonyl)-3,10-bis(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1(16),12,14-triene (1.02 g, 1.24 mmol), thiophenol (0.41 g, 3.72 mmol) and K2CO3 (1.7 g, 12.5 mmol). The crude material was purified by flash chromatography on a silica gel column using CH2Cl2 and then MeOH, 15:1 MeOH—NH4OH (30%) as eluents to give 0.45 g (80%) of the title compound as a pale yellow foam.

Provenance & Evidence