Marcellomycin → 21288-61-9

Participants

Reaction Steps

The drug (75 mg) is refluxed in methanolic HCl (25 mL, 0.1 N) for two hours. At the end of this Marcellomycin (75 mg, 0.175 mmol) is dissolved in methanolic HCl (25 mL, 0.1N) and refuxed at 50° C. for two hours. At the end of this time the reaction mixture is concentrated under vacuum and purified by preparative thin layer chromatography (15% methanol-chloroform). The aglycone ε-pyrromycinone is isolated as a bright red solid (21 mg, 54% yield).

Provenance & Evidence