HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → Methyl-[5-methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 7-Chloro-5-methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]pyrimidine | HCID 21255044 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Methyl-[5-methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-amine | HCID 21255048 | — |
Reaction Steps
In an analogous manner to that described in Example 3, from 7-chloro-5-methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl) -pyrazolo[1,5-a]pyrimidine and methylamine in EtOH there was obtained methyl-[5-methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-amine as colorless crystals, m.p. >230°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194410B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-dabd8f78d52d4b419eaafd6c91958f32 |
| Source note | uspto-grants-2001_02 |