HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-Methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]-pyrimidin-7-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 7-Chloro-5-methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]pyrimidine | HCID 21255044 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]-pyrimidin-7-ylamine | HCID 21255027 | — |
Reaction Steps
In an analogous manner to that described in Example 4, from 7-chloro-5-methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]pyrimidine and NH3 in MeOH there was obtained 5-methyl-2-methylsulphanyl-3-(toluene-4-sulphonyl)-pyrazolo[1,5-a]-pyrimidin-7-ylamine as colorless crystals, m.p. >230°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194410B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-581011d955684a519ee1a966e8cf0d61 |
| Source note | uspto-grants-2001_02 |