Dimethylamine → HCID 9865946, compound

HRID 636397Notes

Reaction equation

HRID 636397 reaction equation
Cl[C:2]1[N:7]2[N:8]=[C:9]([S:23][CH3:24])[C:10]([S:11]([C:14]3[CH:19]=[CH:18][C:17]([CH:20]([CH3:22])[CH3:21])=[CH:16][CH:15]=3)(=[O:13])=[O:12])=[C:6]2[N:5]=[C:4]([CH3:25])[CH:3]=1.[CH3:26][NH:27][CH3:28]>CCO>[CH:20]([C:17]1[CH:16]=[CH:15][C:14]([S:11]([C:10]2[C:9]([S:23][CH3:24])=[N:8][N:7]3[C:2]([N:27]([CH3:28])[CH3:26])=[CH:3][C:4]([CH3:25])=[N:5][C:6]=23)(=[O:12])=[O:13])=[CH:19][CH:18]=1)([CH3:22])[CH3:21]

Participants

4

Reactant 2

HCID 674DimethylamineHCID 21255018HCID 21255018, compound

Product 1

HCID 9865946HCID 9865946, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In an analogous manner to that described in Example 5, from 7-chloro-3-(4-isopropyl-benzenesulphonyl)-5-methyl-2-methylsulphanyl-pyrazolo[1,5-a]pyrimidine and dimethyl-amine in EtOH there was obtained [3-(4-isopropyl-benzenesulphonyl)-5-methyl-2-methylsulphanyl-pyrazolo[1,5-a]pyrimidin-7-yl]-dimethyl-amine as colorless crystals, m.p. 222-224°.

Sources & evidence

ORD record
ord-8f5dc671c037474da318c3a7b55723e1
Source dataset
uspto-grants-2001_02
Patent number
US06194410B1

Reaction notes

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