Ammonia → HCID 21254904, compound

HRID 636401Notes

Reaction equation

HRID 636401 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[C:12]([S:22][CH3:23])=[N:13][N:14]3[C:19](Cl)=[CH:18][C:17]([CH3:21])=[N:16][C:15]=23)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH3:24]>CO>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[C:12]([S:22][CH3:23])=[N:13][N:14]3[C:19]([NH2:24])=[CH:18][C:17]([CH3:21])=[N:16][C:15]=23)(=[O:10])=[O:9])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 212550193-(4-Bromo-benzenesulphonyl)-7-chloro-5-methyl-2-methylsulphanyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 21254904HCID 21254904, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In an analogous manner to that described in Example 4, from 3-(4-bromo-benzenesulphonyl)-7-chloro-5-methyl-2-methylsulphanyl-pyrazolo[1,5-a]pyrimidine and NH3 in MeOH there was obtained 3-(4-bromo-benzenesulphonyl)-5-methyl-2-methylsulphanyl-pyrazolo[1,5-a]pyrimidin-7-ylamine as colorless crystals, m.p.>230°.

Sources & evidence

ORD record
ord-8bae9dbca44a462eaee1c74595531bba
Source dataset
uspto-grants-2001_02
Patent number
US06194410B1

Reaction notes

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