Dimethylamine → HCID 21254957, compound

HRID 636403Notes

Reaction equation

HRID 636403 reaction equation
Cl[C:2]1[N:7]2[N:8]=[C:9]([S:24][CH3:25])[C:10]([S:11]([C:14]3[CH:23]=[CH:22][C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=3)(=[O:13])=[O:12])=[C:6]2[N:5]=[C:4]([CH3:26])[CH:3]=1.[CH3:27][NH:28][CH3:29]>CCO>[CH3:27][N:28]([CH3:29])[C:2]1[N:7]2[N:8]=[C:9]([S:24][CH3:25])[C:10]([S:11]([C:14]3[CH:23]=[CH:22][C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=3)(=[O:13])=[O:12])=[C:6]2[N:5]=[C:4]([CH3:26])[CH:3]=1

Participants

4

Reactant 2

HCID 674DimethylamineHCID 212550017-Chloro-5-methyl-2-methylsulphanyl-3-(naphthalene-2-sulphonyl)-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 21254957HCID 21254957, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In an analogous manner to that described in Example 6, from 7-chloro-5-methyl-2-methylsulphanyl-3-(naphthalene-2-sulphonyl)-pyrazolo[1,5-a]pyrimidine and dimethyl-amine in EtOH there was obtained dimethyl-[5-methyl-2-methylsulphanyl-3-(naphthalene-2-sulphonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-amine as colorless crystals, m.p.>230°.

Sources & evidence

ORD record
ord-7c8ba09e84e04e848bca8d4ed3158221
Source dataset
uspto-grants-2001_02
Patent number
US06194410B1

Reaction notes

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