Ammonia → HCID 9885244, compound

HRID 636408Notes

Reaction equation

HRID 636408 reaction equation
[C:1]1([S:7]([C:10]2[C:11]([S:23][CH3:24])=[N:12][N:13]3[C:18](Cl)=[C:17]4[CH2:20][CH2:21][CH2:22][C:16]4=[N:15][C:14]=23)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH3:25]>CO>[C:1]1([S:7]([C:10]2[C:11]([S:23][CH3:24])=[N:12][N:13]3[C:18]([NH2:25])=[C:17]4[CH2:20][CH2:21][CH2:22][C:16]4=[N:15][C:14]=23)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 21254931HCID 21254931, compound

Product 1

HCID 9885244HCID 9885244, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In an analogous manner to that described in Example 4) from 3-benzenesulphonyl-8-chloro-2-methylsulphanyl-6,7-dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine and NH3 in MeOH there was obtained 3-benzenesulphonyl-2-methylsulphanyl-6,7-dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidin-8-ylamine as colorless crystals, m.p.>230°.

Sources & evidence

ORD record
ord-6621c720b28e44c1985f2a154ad58646
Source dataset
uspto-grants-2001_02
Patent number
US06194410B1

Reaction notes

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