Ammonia → HCID 21255015, compound

HRID 636410Notes

Reaction equation

HRID 636410 reaction equation
[C:1]1([S:7]([C:10]2[C:11]([S:23][CH3:24])=[N:12][N:13]3[C:18](Cl)=[CH:17][C:16]([CH:20]([CH3:22])[CH3:21])=[N:15][C:14]=23)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH3:25]>CO>[C:1]1([S:7]([C:10]2[C:11]([S:23][CH3:24])=[N:12][N:13]3[C:18]([NH2:25])=[CH:17][C:16]([CH:20]([CH3:22])[CH3:21])=[N:15][C:14]=23)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 21255003HCID 21255003, compound

Product 1

HCID 21255015HCID 21255015, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In an analogous manner to that described in Example 4, from 3-benzenesulphonyl-7-chloro-5-isopropyl-2-methylsulphanyl-pyrazolo[1,5-a]pyrimidine and NH3 in MeOH there was obtained 3-benzenesulphonyl-5-isopropyl-2-methylsulphanyl-pyrazolo[1,5-a]pyrimidin-7-ylamine as colorless crystals, m.p. 210-211°.

Sources & evidence

ORD record
ord-5fbb93b6025f4f2a8e1d472917022a1f
Source dataset
uspto-grants-2001_02
Patent number
US06194410B1

Reaction notes

Loading…