Ammonia → HCID 21255032, compound

HRID 636416Notes

Reaction equation

HRID 636416 reaction equation
Cl[C:2]1[N:7]2[N:8]=[C:9]([CH2:22][CH3:23])[C:10]([S:11]([C:14]3[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=3)(=[O:13])=[O:12])=[C:6]2[N:5]=[C:4]([CH3:24])[CH:3]=1.[NH3:25]>CO>[CH2:22]([C:9]1[C:10]([S:11]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)(=[O:13])=[O:12])=[C:6]2[N:5]=[C:4]([CH3:24])[CH:3]=[C:2]([NH2:25])[N:7]2[N:8]=1)[CH3:23]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 21255020HCID 21255020, compound

Product 1

HCID 21255032HCID 21255032, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In an analogous manner to that described in Example 4, from 7-chloro-2-ethyl-3-(4-methoxy-benzenesulphonyl)-5-methyl-pyrazolo[1,5-a]pyrimidine and NH3 in MeOH there was obtained 2-ethyl-3-(4-methoxy-benzenesulphonyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine as colorless crystals, m.p. 186-188°.

Sources & evidence

ORD record
ord-0dce5162a6bd4e9d8e236ef3c9a249d6
Source dataset
uspto-grants-2001_02
Patent number
US06194410B1

Reaction notes

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