Sodium Hydroxide → Benzoic acid, 2-nitro-3-(phenylmethoxy)-

Participants

Reaction Conditions

Reaction Steps

To a suspension of benzyl 3-benzyloxy-2-nitrobenzoate (640 mg) in ethanol (5 ml) was added 1N sodium hydroxide solution (1.94 ml) at ambient temperature, and the mixture was stirred at 60° C. for 1 hour. The reaction mixture was adjusted to pH 4, and the resulting precipitates were collected by filtration and dried to give 3-benzyloxy-2-nitrobenzoic acid (439 mg).

Provenance & Evidence