Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 636517Generated: October 26, 2026

methyl 4-[(Z)-2-(4-pyridyl)vinyl]benzoate → Methyl 4-[2-(4-pyridyl)ethyl]benzoate

https://huagongshe.com/reaction/636517

Reaction equation

Participants

RoleNameHCIDCharge
Reactantmethyl 4-[(Z)-2-(4-pyridyl)vinyl]benzoateHCID 70244616—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductMethyl 4-[2-(4-pyridyl)ethyl]benzoateHCID 2125478593.8%

Reaction Steps

To a solution of methyl 4-[(Z)-2-(4-pyridyl)vinyl]benzoate (570 mg) in methanol (5.7 ml) was added 10% palladium on carbon, and the mixture was stirred for 4 hours at ambient temperature under hydrogen atmosphere. Insoluble material was filtered off, and the filtrate was concentrated in vacuo. The residue was crystallized with n-hexane to give methyl 4-[2-(4-pyridyl)ethyl]benzoate (539 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06194396B1
Source datasetuspto-grants-2001_02
ORD IDord-70ade6e382b746f3bc0f8ec337b75590
Source noteuspto-grants-2001_02