HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 4-[(Z)-2-(4-pyridyl)vinyl]benzoate → Methyl 4-[2-(4-pyridyl)ethyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 4-[(Z)-2-(4-pyridyl)vinyl]benzoate | HCID 70244616 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 4-[2-(4-pyridyl)ethyl]benzoate | HCID 21254785 | 93.8% |
Reaction Steps
To a solution of methyl 4-[(Z)-2-(4-pyridyl)vinyl]benzoate (570 mg) in methanol (5.7 ml) was added 10% palladium on carbon, and the mixture was stirred for 4 hours at ambient temperature under hydrogen atmosphere. Insoluble material was filtered off, and the filtrate was concentrated in vacuo. The residue was crystallized with n-hexane to give methyl 4-[2-(4-pyridyl)ethyl]benzoate (539 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194396B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-70ade6e382b746f3bc0f8ec337b75590 |
| Source note | uspto-grants-2001_02 |