HCID 21255220, compound → HCID 21255233, compound

HRID 636542Notes

Reaction equation

HRID 636542 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[C:13]([C:14]([O:16][CH3:17])=[O:15])=[C:12]([CH3:18])[NH:11][C:10]3[C:19](=[O:22])[O:20][CH2:21][C:9]2=3)=[CH:4][CH:3]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:13]([C:14]([O:16][CH3:17])=[O:15])=[C:12]([CH3:18])[N:11]=[C:10]3[C:19](=[O:22])[O:20][CH2:21][C:9]=23)=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 21255220HCID 21255220, compound

Product 1

HCID 21255233HCID 21255233, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6344DichloromethaneSolvent

Procedure

Corresponding to Example 1, 1.5 g (3.92 mmol) of methyl 1,4,5,7-tetrahydro-4-(4-chlorophenyl)-2-methyl-7-oxo-furo[3,4-b]-pyridine-3-carboxylate in 350 ml of methylene chloride are reacted with 7.5 g of manganese dioxide to give 0.94 g (63% of theory) of the title compound.

Sources & evidence

ORD record
ord-daf096cc466c42689c6b7a6f350f1ec0
Source dataset
uspto-grants-2001_02
Patent number
US06194428B1

Reaction notes

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