Acetic Acid → HCID 343062, compound

Participants

Reaction Steps

To a solution of 4-cyanobenzaldehyde (392.9 mg, 3.00 mmol) and t-butylamine (227.3 mg, 3.10 mmol) in 1,2-dichloroethane (12 ml) was added sodium triacetoxyborohydride (0.8567 g, 4.04 mmol) and stirred for 3 hours. Acetic acid (0.17 ml, 2.95 mmol) was added to the mixture and stirred for 2.5 hours. The mixture was added to sat. NaHCO3 aqueous solution, extracted three times with ethyl acetate and dried over MgSO4. The solvent was evaporated to give the crude title compound (595.3 mg).

Provenance & Evidence