2-Cyano-4-methylpyridine → HCID 21366762, compound

HRID 63676Notes

Reaction equation

S1[CH:5]=[CH:4][N:3]=[C:2]1[C:6]([NH2:8])=[NH:7].[CH3:9][C:10]1C=CN=C(C#N)[CH:11]=1>>[CH3:11][C:10]1[CH:5]=[CH:4][N:3]=[C:2]([C:6]([NH2:8])=[NH:7])[CH:9]=1

Participants

Reactant 2

HCID 887392-Cyano-4-methylpyridine

HCID 108879112-Thiazolecarboximidamide

Product 1

HCID 21366762HCID 21366762, compound

Procedure

4-Methyl-pyridine-2-carboxamidine (Compound A2) was prepared in analogy to compound thiazole-2-carboxamidine with the procedure shown in Scheme 5 by using 4-methyl-pyridine-2-carbonitrile instead of thiazole-2-carbonitrile. MS: calc'd (MH+) 136, measured (MH+) 136.

Sources & evidence

ORD record: ord-4fbdcc70588c4b0d8ec5696d8b97d570
Source dataset: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09447086B2

Reaction notes

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