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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63678Generated: October 26, 2026

Bromopinacolone → 4-tert-Butyl-thiazole-2-carboxamidine

https://huagongshe.com/reaction/63678

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromopinacoloneHCID 21642—
Reactant4-Cyclopropyl-thiazole-2-carboxamidineHCID 90000916—
Product4-tert-Butyl-thiazole-2-carboxamidineHCID 83385723—

Reaction Steps

4-tert-Butyl-thiazole-2-carboxamidine (Compound N) was prepared in analogy to Compound M with procedure shown in Example 10 by using 1-bromo-3,3-dimethyl-butan-2-one instead of 2-bromo-1-cyclopropyl-ethanone. MS: calc'd (MH+) 184, measured (MH+) 184.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447086B2
Source datasetuspto-grants-2016_09
ORD IDord-7fe6473a628d4548aa1af40b68f3751d
Source noteuspto-grants-2016_09