4-(Bromoacetyl)benzonitrile → HCID 70224701, compound

Participants

Reaction Steps

Using the same procedure as described in Example 2C, the reaction of the title compound of 30A (10.3 mmol) and 4-cyanophenacyl bromide (11.3 mmol) in the presence of potassium bis(trimethylsilyl)amide (11.3 mmol) generated the title compound of 30B, 4.82 g (8.4 mmol, 84% yield).

Provenance & Evidence