反应详情

Using the same procedure as described in Example 1C, the title compound of 53C (0.548 g, 0.558 mmol) and 4-cyanophenacyl bromide (138 mg, 0.614 mmol) in the presence of potassium bis(trimethylsilyl)-amide (129 mg, 0.614 mmol) reacted to yield the title compound of 53D, after chromatographic purification, 0.46 g (0.41 mmol, 73% yield).