HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → 1-Pyrrolidinamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 1-Pyrrolidinamine | HCID 27946 | — |
| Reactant | Butanediol | HCID 165788 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Pyrrolidinamine | HCID 27946 | — |
| Product | Tetrahydropyridazine | HCID 21255899 | — |
Reaction Steps
Thus, 1-aminopyrrolidine is synthesized from hydrazine hydrohalogenic acid salt and butane diol or tetrahydrofuran, and by oxidizing 1-aminopyrrolidine with an oxidizing agent to form tetrahydropyridazine, and next, the tetrahydropyridazine is hydrogenated by using a noble metal catalyst to produce with industrial and economical advantages hexahydropyridazine which is very useful as an intermediate for agricultural chemicals or medicines.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194577B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-4e1ac66220174ddb9e6725d8eea37d67 |
| Source note | uspto-grants-2001_02 |