HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 636928Generated: October 31, 2026
Hydrochloric Acid → 1-Aminoisoquinoline-6-carboxylic acid hydrochloride
https://huagongshe.com/reaction/636928
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | [1-(Benzoylamino)-6-isoquinolinyl]carboxylic acid | HCID 22665699 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 1-Aminoisoquinoline-6-carboxylic acid hydrochloride | HCID 69781233 | — |
Reaction Steps
A mixture of 445 mg [1-(benzoylamino)-6-isoquinolinyl]carboxylic acid, 10 mL of acetic acid and 20 mL of 4N hydrochloric acid was heated at 100° C. for one day. The reaction mixture was concentrated and coevaporated with 0.5N hydrochloric acid. The resulting residue was triturated with diethyl ether to yield 341 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06194409B1 |
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| Source dataset | uspto-grants-2001_02 |
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| ORD ID | ord-f9d7118992f44340a9680b0c5e292922 |
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| Source note | uspto-grants-2001_02 |
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