HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 22867972, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Potassium bisulfate | HCID 516920 | — |
| Reactant | HCID 53818679 | HCID 53818679 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 22867972 | HCID 22867972 | 83% |
Reaction Steps
A mixture of 2-(R)-methanesulfonylamino-3-phenyl-propionic acid methyl ester (0.90 g) and 0.10 g of LiOH in 10 mL of methanol and 1 mL of water was stirred for 16 h at ambient temperature. KHSO4 was added, the volatiles were pumped off followed by addition of water, extraction with dichloromethane and removal of the solvent. Yield: 0.70 g (83%) of the title compound as a colorless oil. (−)-APCI-MS: 242 ([M-H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194409B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-dd8a155878a740adb13fc3772404be5f |
| Source note | uspto-grants-2001_02 |