HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 2-Methoxy-5-(1H-tetrazol-1-ylmethyl)benzoyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-methoxy-5-(1H-tetrazol-1-ylmethyl)benzoic acid | HCID 18464585 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Methoxy-5-(1H-tetrazol-1-ylmethyl)benzoyl Chloride | HCID 18464956 | — |
Reaction Steps
Combine 2-methoxy-5-(1H-tetrazol-1-ylmethyl)benzoic acid (0.35 g, 1.5 mmol) and dichloromethane (25 mL). Add dropwise oxalyl chloride (0.21 mL, 2.35 mmol) followed by dimethylformamide (5 drops). After 4 hours, evaporate in vacuo and dry to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194406B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-acebdeeaf31148e58af10d22a3c111b6 |
| Source note | uspto-grants-2001_02 |