HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 2-Methoxy-5-(1H-triazol-1-ylmethyl)benzoyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-methoxy-5-(1H-triazol-1-ylmethyl)benzoic acid | HCID 18465050 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Methoxy-5-(1H-triazol-1-ylmethyl)benzoyl Chloride | HCID 18464525 | — |
Reaction Steps
Combine 2-methoxy-5-(1H-triazol-1-ylmethyl)benzoic acid (0.22 g, 0.94 mmol) and dichloromethane (50 mL). Add dropwise oxalyl chloride (0.14 mL, 1.6 mmol) followed by dimethylformamide (5 drops). After 4 hours, evaporate in vacuo and dry to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194406B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-7bee2a33b9a140ec9aa44f33ba58ef02 |
| Source note | uspto-grants-2001_02 |