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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 637201Generated: October 27, 2026

1-Chloro-3-methyl-2-butene → 1-(3,4,5-Trimethoxybenzoyl)-3-(2-(4-(1-(3-methylbut-2-en-1-yl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine

https://huagongshe.com/reaction/637201

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-3-methyl-2-buteneHCID 10429—
Reactant1-(3,4,5-trimethoxybenzoyl)-3-(2-(4-(1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidineHCID 18464478—
Product1-(3,4,5-Trimethoxybenzoyl)-3-(2-(4-(1-(3-methylbut-2-en-1-yl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidineHCID 18465005—

Reaction Steps

Prepare by the method of Example 35.1 using 1-(3,4,5-trimethoxybenzoyl)-3-(2-(4-(1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine and 1-chloro-3-methylbut-2-ene to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06194406B1
Source datasetuspto-grants-2001_02
ORD IDord-1dfb0290c7824a42a92449a5c099c5c0
Source noteuspto-grants-2001_02