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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 637206Generated: October 31, 2026

3-(2-(4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine hydrochloric acid → HCID 18465074, compound

https://huagongshe.com/reaction/637206

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-(4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine hydrochloric acidHCID 18464957—
Reactant5-Cyano-2-methoxybenzoic acidHCID 21942568—
ProductHCID 18465074HCID 18465074—

Reaction Steps

Prepare by the method of Example 56.1 using 2-methoxy-5-cyanobenzoic acid and 3-(2-(4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine hydrochloric acid salt (prepared from (−)-3-(2-hydroxyethyl)-3-phenylpyrrolidine(R,R)-di-p-anisoyltartaric acid salt) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06194406B1
Source datasetuspto-grants-2001_02
ORD IDord-45a1b68add494b729aaf778a49905046
Source noteuspto-grants-2001_02