Piperidine → HCID 70490507, compound

Participants

Reaction Steps

3.21 g of bishydroxymethylene-3,4-dichlorophenyl-hydroxymalonic acid diamide (0.01 mol) are kept at 50° C. with 3 g of piperidine and 3 drops of boron trifluoride in 50 ml of dioxane for 8 hours. After the addition of 0.5 ml of triethylamine, the mixture is evaporated down, the residue is taken up with ether, and the product is filtered off under suction. 6.7 g of bis-piperidinomethylene-3,4-dichlorophenyl-hydroxymalonic acid diamide (73% of theory) of melting point 195° C. are obtained.

Provenance & Evidence