2,2-Dimethyl-4-oxo-4-phenylbutanoic acid → HCID 20256872, compound

HRID 637317Notes

Reaction equation

HRID 637317 reaction equation
[C:1]([CH2:9][C:10]([CH3:15])([CH3:14])[C:11]([OH:13])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl-:16].[Al+3].[Cl-].[Cl-]>>[Cl:16][C:4]1[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=1)[C:1]([CH2:9][C:10]([CH3:15])([CH3:14])[C:11]([OH:13])=[O:12])=[O:8]

Participants

3

Reactant 2

HCID 5698152,2-Dimethyl-4-oxo-4-phenylbutanoic acidHCID 6451240Aluminum(III) Chloride

Product 1

HCID 20256872HCID 20256872, compound

Procedure

Using the procedure of T. Joyima et al., Bull. Chem. Soc. Jap., 52(8) 2441-2442 (1979), 3-benzoyl-2,2-dimethylpropionic acid was converted into the title compound by chlorination in the presence of excess aluminum chloride.

Sources & evidence

ORD record
ord-07873de56e604ea682decaa949f33e42
Source dataset
uspto-grants-1985_12
Patent number
US04556670

Reaction notes

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